Abstract
RESULTS: The osteoporotic group showed significant decrease of BMI ( p<.01), increased BMC (p<.01) and decreased ALP (p<.01) concentration. There was a significant positive correlation found between serum cortisol and salivary cortisol concentrations (r=.265, p<0.05). whereas BMI showed an independent relationship with the osteoporosis group (β=.663, p=.038). ALP concentration was also found to be a useful prognostic factor of osteoporosis (Osteoporotic group: AUC=0.724, sensitivity=64.3%, specificity=58.8%). Serum cortisol and salivary cortisol concentrations were not significantly related in the osteoporotic group, but showed a significant positive correlation as predictors of osteoporosis. CONCLUSIONS: Changes in bone metabolic marker of normal and osteoporotic patients showed a different pattern. In addition, it had a positive effect on bone mineral density improvement, but not on cortisol concentration.
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