Abstract
IntroductionThe appearance of preeclampsia (PE) would comprise the alteration of endothelial function and activation of the inflammatory response, leading to placental hypoperfusion. The neutrophil/lymphocyte ratio (NLR) and the polymorphonuclear/monomorphonuclear ratio (PMR) could measure the underlying inflammatory component and predict the onset of the disorder. Material and methodsObservational, analytical, case and control study. We retrospectively analysed medical records of pregnant women, hospitalized for hypertension registers. The patients were divided into Group1=with PE development, and Group2=without PE development. Results110 patients were included: Group1=58.2% and Group2=41.8%, observing differences between the NLR means (P=.01) and PMR means (P=.02). An NLR ≥4.5 (P=.002; OR=3.9; 95%CI=1.6-9.5) and a PMR ≥3 (P=.004; OR=3.5; 95%CI=1.4-8.4) was related with PE. ConclusionThe elevation of NLR and PMR in hypertensive pregnant patients, could be considered indicators for the development of PE.
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