Abstract
ObjectiveTo evaluate the performance of the FRAX and QFracture tools in a group of type 2 diabetes mellitus (T2DM) patients. Material and methodsA cross-sectional study including 78 patients with type 2 diabetes. Lumbar spine and femoral bone mineral density (BMD) were measured by dual X-Ray absorptiometry (Hologic QDR 4500). Ten-year major osteoporotic fracture risk and hip fracture risk were calculated using the FRAX and QFracture tools. Results were analysed using the SPSS 15.0 program. ResultsMean age was 57.8 years (57.8±6.4). It was found that 22.4% of patients had densitometric criteria for osteoporosis, and 9% had a previous fracture. Prevalent radiographic vertebral fractures were detected in 27.7%. Few patients were selected for treatment according to FRAX: 2.6% for major osteoporotic fracture, 5.1% after introducing hip BMD (p.002) and 2.6% for hip fracture risk only if hip BMD was added. Using QFracture, 3.8% of patients had a high probability of osteoporotic fracture, and 1.3% a hip fracture. ConclusionsIn our group of type 2 diabetes mellitus patients, a low percentage were selected for treatment using the FRAX tool or QFracture tool despite the high risk of fracture demonstrated by high vertebral fracture rate.
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