Abstract
Changes in lysosomal enzyme activities were measured during early pregnancy in implantation and nonimplantation uterine segments. Increases in arylsulfatase B and acid phosphatase activity some 48 h after initial blastocyst contact with the endometrium appeared to result from decidualization of the endometrial stroma. In contrast to the decrease previously observed in cathepsin D activity, no change was observed in cathepsin B,, another lysosomal protease. The diversity of changes in lysosomal enzyme activities suggests the involvement of these enzymes in early stromal differentiation rather than in ovum implantation.
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