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Abstract
When detected early, uterine cervical cancer is one of the most successfully treatable forms of cancer. The diagnostic accuracy of the standard method, the Pap smear test followed by colposcopy, remains unsatisfactory. To improve detection of early-stage cervical cancer, new diagnostic tools for uterine cervical intraepithelial neoplasm (CIN) need to be developed. Magnifying endoscopy with narrow- band imaging (ME-NBI), which allows the visualization of the micro-structure as well as micro-vascularity of the mucosal surface, has excellent diagnostic ability for early gastrointestinal neoplasms. In our previous investigation, ME-NBI was efficacious for diagnosis of CIN. We herein report two notable cases of CIN3 that were diagnosed by ME-NBI that were not detected by colposcopy. These cases illustrate the usefulness of ME-NBI for diagnosis of early-stage uterine cervical neoplasms.
Highlights
When detected early, uterine cervical cancer is one of the most successfully treatable forms of cancer
The of microvessels can be evaluated by Magnifying endoscopy with narrow- band imaging (ME-NBI), and the grade of cervical intraepithelial neoplasm (CIN) is expected to be distinguished according to the intrapapillary capillary loop (IPCL) classification [8]
White epithelial neoplasm is endoscopically defined as a wellevaluated by ME-NBI, and the grade of CIN is expected to be distinguished according to the IPCL
Summary
Uterine cervical cancer is one of the most successfully treatable forms of cancer. NBI image indicated abnormal a suspicious abnormal lesion in the 7 ME-NBI the with acetic showed no application of acetowhite epithelium that area, whereas with acetic acid revealed atypical acid revealed architectures the atypical with micro-vascular architectures witharrangement, dilatation, crawling, micro-vascular dilatation, crawling, irregular and caliberirregular change arrangement, and caliber change (d) NBI, whichtend is specific light absorbed hemoglobin, can enhance the superficial vessels as absorbed a black color.
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