Abstract

Angioleiomyomas are benign mesenchymal tumours commonly occurring in the subcutis of extremities. They are typically composed of interlacing fascicles of smooth muscle cells with intersecting vascular channels. Angioleiomyomas of the uterus are rare with only very few case reports available in literature. Herein, we report a case of this rare entity in a 47-year-old woman owing to its highly unusual features of cellular atypia, raised CA-125 levels, and pseudo Meigs syndrome.

Highlights

  • Angioleiomyoma is a rare and distinct variant of leiomyoma [1]

  • Uterine angioleiomyomas morphologically resemble those in the subcutis, the latter commonly occurring in the extremities, head, and trunk

  • To the best of our knowledge, this is the first documented case of a uterine angioleiomyoma with atypia presenting with raised CA-125 levels and pseudo Meigs syndrome

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Summary

Introduction

Angioleiomyoma is a rare and distinct variant of leiomyoma [1]. Uterine angioleiomyomas morphologically resemble those in the subcutis, the latter commonly occurring in the extremities, head, and trunk. Pseudo Meigs syndrome is a rare syndrome typically described with pelvic tumors (excluding ovarian fibromas) presenting with ascites and left pleural effusion. Pseudo Meigs syndrome and raised CA125 levels have been rarely described in association with typical uterine leiomyomas. To the best of our knowledge, this is the first documented case of a uterine angioleiomyoma with atypia presenting with raised CA-125 levels and pseudo Meigs syndrome

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