Uso terapêutico do plasma rico em plaquetas na prevenção de cicatrizes inestéticas em animais e humanos

Abstract

The development of skin lesions can cause the presence of scars, which are associated to aesthetic issues, especially in women. The use of Platelet-Rich Plasma (PRP) in post-surgery showed a better degree of healing, with less marks and discomfort due to the production of anti-inflammatory mediators and better tissue repair. Our objective is to promote a survey of the results obtained by published studies regarding the effectiveness of the therapeutic use of PRP in the healing of wounds in animals and humans. To achieve our aim, we conducted a review, with articles from digital platforms, from 2000 and 2023, which used people or animals, who used RPR and who had a description of the effectiveness of the procedure. There were identified 16/94 articles that met the criteria, where in addition to humans, research also used rabbits, rodents, dogs, and horses. PRP was prepared in heterologous, homologous, and autologous ways, and used in lesions with delayed healing, burns, as an adjuvant in grafting, in cutaneous tissue with an accelerated aging process and in postoperative scars from plastic surgery. Regardless the administration, all studies agreed that its repairing effect is greater in the early stages of healing. With this, we highlight that PRP can be a good therapeutic resource in healing complications, and although there is still no established protocol for collection and prepare, it presents promising results in the surgical postoperative period. However, we suggest that more studies must be carried out, as well as a protocol be standardized to obtain and use PRP in a safe and reliable way.