Uso de calcipotriol en psoriasis ungueal infantil: descripción de 12 casos

Abstract

IntroductionPsoriasis affects 0.5-0.7% of children in Europe, with a prevalence of nail involvement of 20 - 40%. Nail psoriasis has a negative impact on quality of life. Therapeutic options include topical products, procedures, oral drugs and biological agents. However, there is limited evidence on the therapeutic management of nail psoriasis in children. Topical calcipotriol has shown to be a promising tool. The present study aims to evaluate a new topical scheme using the description of 12 paediatric patients with nail psoriasis, treated with a topical calcipotriol with and without betamethasone for 4 months. MethodologyThe study included 12 patients with a clinical diagnosis of nail psoriasis that had not received previous treatment. Topical treatment was applied on affected nails using calcipotriol with betamethasone applied twice a day for 1 month. Topical calcipotriol only was then applied in the mornings with calcipotriol and betamethasone applied at night for 1 month, Finally topical calcipotriol only was applied twice a day for 2 months. ResultsAll patients responded satisfactorily to the therapy scheme, without developing adverse effects. The nails of hands responded in half the time as those of the feet. Disorders of the matrix responded more quickly, and problems of the nail bed, the subungual hyperkeratosis, had the slowest resolution. ConclusionThe proposed scheme is a rational, accessible, easy to use and safe treatment for management of nail psoriasis in children.