Abstract
The pulse contour method is often used with the Windkessel model to measure stroke volume. We used a digital pressure and flow sensors to detect the parameters of the Windkessel model from the pulse waveform. The objective of this study was to assess the stability and accuracy of this method by making use of the passive leg raising test. We studied 24 healthy subjects (40 ± 9.3 years), and used the Medis® CS 1000, an impedance cardiography, as the comparing reference. The pulse contour method measured the waveform of the brachial artery by using a cuff. The compliance and resistance of the peripheral artery was detected from the cuff characteristics and the blood pressure waveform. Then, according to the method proposed by Romano et al., the stroke volume could be measured. This method was implemented in our designed blood pressure monitor. A passive leg raising test, which could immediately change the preloading of the heart, was done to certify the performance of our method. The pulse contour method and impedance cardiography simultaneously measured the stroke volume. The measurement of the changes in stroke volume using the pulse contour method had a very high correlation with the Medis® CS 1000 measurement, the correlation coefficient of the changed ratio and changed differences in stroke volume were r2 = 0.712 and r2 = 0.709, respectively. It was shown that the stroke volume measured by using the pulse contour method was not accurate enough. But, the changes in the stroke volume could be accurately measured with this pulse contour method. Changes in stroke volume are often used to understand the conditions of cardiac preloading in the clinical field. Moreover, the operation of the pulse contour method is easier than using impedance cardiography and echocardiography. Thus, this method is suitable to use in different healthcare fields.
Highlights
The hemodynamic characteristics of hearts have shown that high correlation with cardiovascular diseases, such as blood pressure (BP), cardiac output (CO), and systemic vascular resistance (SVR).Stroke volume (SV) and CO are fundamental measures of cardiovascular functions, and are essential for the accurate understanding of cardiovascular pathophysiology, the guidance of fluid, and vasoactive therapies [1]
We studied the accuracy of the SV and the changes in the SV, using the pulse contour method before and during the Passive leg raising (PLR) test
We found that the dicrotic notch of pulse contour occurring time, t3, during the PLR test was longer than the time before the PLR test
Summary
The hemodynamic characteristics of hearts have shown that high correlation with cardiovascular diseases, such as blood pressure (BP), cardiac output (CO), and systemic vascular resistance (SVR).Stroke volume (SV) and CO are fundamental measures of cardiovascular functions, and are essential for the accurate understanding of cardiovascular pathophysiology, the guidance of fluid, and vasoactive therapies [1]. Patients who undergo high-risk surgical procedures need continuous post-surgery monitoring, and early hemodynamic optimization has shown to be very important, as it results in significantly reduced mortality [2,3]. The oscillometry and auscultation methods are often used to measure BP [4], and echocardiography [5] and impedance cardiography (ICG) [6] are noninvasive methods to measure SV These instruments, used for the echocardiography and the ICG techniques, are all expensive and need an expert to process the results gained from them. Less invasive and noninvasive measurement techniques are available, they do not provide precise enough results to satisfy clinical requirements. If it was possible to measure the changes in SV using a simple and easy technique, this technique would be the preferred method in health care
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