Abstract

BackgroundIn obese children, lipophilic medications should be dosed to total body weight (TBW) and hydrophilic medications to ideal body weight (IBW). During emergencies, these weights need to be estimated to ensure that urgent drug therapy is accurate and safe. The Mercy method is a well-established weight estimation system that has recently been adapted to provide estimations of body length in children. It was therefore conceivable that this could be further modified to provide estimations of IBW.MethodsA model was developed a priori using the Mercy method’s humeral length (HL) segments to predict IBW. The accuracy of this model was then tested in a sample of 13,134 children from the National Health and Nutrition Examination Survey (NHANES) datasets. The accuracy of IBW estimation was determined from the percentage of estimations falling within 10% (p10) and 20% (p20) of true IBW. The model was also tested to see the accuracy of the detection of obesity in the study sample.ResultsFrom the sample of 13,134 children, a subset of 1,318 obese children were identified. In this subset, the new Mercy method model achieved an IBW estimation accuracy p10 of 66.9% and a p20 of 95.1%. For the detection of the obese child, the model had a sensitivity of 88.6% and a specificity of 75.8%.ConclusionsThis study established that the Mercy method can be modified to provide a reasonably accurate estimation of IBW in obese children, with very few critical errors. The ability of the model to identify the obese child was also reasonably accurate, on a par with other such predictive methods. While other accurate methods of estimating both TBW and IBW exist, such as the Paediatric Advanced Weight Prediction in the Emergency Room eXtra-Long tape (PAWPER XL tape), the modified Mercy method is an acceptable alternative if such other devices are not available.

Highlights

  • The World Health Organization has recommended that the doses of hydrophilic drugs be calculated according to ideal body weight (IBW) in obese children [1]

  • This study established that the Mercy method can be modified to provide a reasonably accurate estimation of IBW in obese children, with very few critical errors

  • While other accurate methods of estimating both total body weight (TBW) and IBW exist, such as the Paediatric Advanced Weight Prediction in the Emergency Room eXtra-Long tape (PAWPER XL tape), the modified Mercy method is an acceptable alternative if such other devices are not available

Read more

Summary

Introduction

The World Health Organization has recommended that the doses of hydrophilic drugs be calculated according to ideal body weight (IBW) in obese children [1] This is necessary in order to prevent potentially harmful overdoses of these medications in these children. During medical emergencies in children - when a child cannot be weighed to determine TBW and there is no time to calculate IBW - it is necessary to be able to estimate both these dose scalars before drugs can be administered [3] Devices such as the Paediatric Advanced Weight Prediction in the Emergency Room eXtraLong tape (PAWPER XL tape) are able to estimate both TBW and IBW accurately in obese children, but the tape might not be available in all settings [4]. Lipophilic medications should be dosed to total body weight (TBW) and hydrophilic medications to ideal body weight (IBW) During emergencies, these weights need to be estimated to ensure that urgent drug therapy is accurate and safe. It was conceivable that this could be further modified to provide estimations of IBW

Objectives
Methods
Discussion
Conclusion
Full Text
Paper version not known

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.