Abstract

EA Erwin, DA Rhoda, M Redmond. J Pediatr Gastroenterol Nutr. 2017;65(5):520–525 This study was designed to develop a model to use food-specific serum immunoglobulin E (IgE) antibodies to predict which patients would have ≥15 eosinophils per high power field (eos/hpf) in the esophagus to help decrease diagnosis and treatment delay for esophageal eosinophilia. There were 2 subsets of patients, 1 exploratory and the other for validation of the predictive model. The exploratory subset included 144 pediatric patients from Nationwide Children’s Hospital seen between April and September 2015, with serum analysis for IgE antibodies to food, and an esophagogastroduodenoscopy with esophageal biopsy. The validation subset included 174 patients with …

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