Abstract
OPINION article Front. Neurol., 05 February 2013Sec. Spinal Cord Medicine https://doi.org/10.3389/fneur.2013.00005
Highlights
New evidence has suggested the Rho signaling pathway as a target for treatment in acute spinal cord injury (SCI)
The article referenced two guideline reviews on SCI and its spontaneous recovery (Fawcett et al, 2007; Steeves et al, 2007). They reported the results of recovery after the application of BA-210 as well
Guidelines were reviews of investigations including those by Kirshblum et al (2004), Waters et al (1993), Geisler et al (2001) and European Multicenter study in Spinal Cord Injury (EMSCI)
Summary
New evidence has suggested the Rho signaling pathway as a target for treatment in acute spinal cord injury (SCI). A “Phase I/IIa Clinical Trial of a Recombinant Rho Protein antagonist in Acute Spinal Cord Injury” by Fehlings et al (2011) has been recently published to evaluate BA-210 in course of SCI. The article referenced two guideline reviews on SCI and its spontaneous recovery (Fawcett et al, 2007; Steeves et al, 2007). They reported the results of recovery after the application of BA-210 as well.
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