Using real-world data to estimate the changing trends in the prevalence and incidence of type 2 diabetes mellitus in Xiamen of China from 2014 to 2019

Lishan Ye,Ting Wu,Xuejun Li,Weiwei He,Xiulin Shi,Qiushi Xu,Lili Han,Guanhua Yao

doi:10.1186/s12902-021-00759-w

Abstract

BackgroundThe prevalence of diabetes is increasing worldwide. Our study aimed to estimate the changing trends in the prevalence and incidence of diagnosed type 2 diabetes mellitus (T2DM) among Xiamen residents and the floating population using real-world data.MethodWe used real-world data from the System of Xiamen Citizens Health Information from 2014 to 2019 to estimate the changing trends in the prevalence and incidence of diagnosed T2DM. The System included the diagnosis of diabetes and the prescription of hypoglycemic drugs. Prevalent cases of T2DM were individuals who were diagnosed with T2DM and/or using hypoglycemic drugs. Incident cases were individuals with diagnosed T2DM and/or using hypoglycemic drugs in 2014 or 2019 who had not been diagnosed and/or did not use hypoglycemic drugs in the past.ResultsIn 2014 and 2019, the prevalence of T2DM in Xiamen was 4.04 and 4.84%, respectively. In 2014 and 2019, the incidence rate of T2DM in Xiamen was 14.1 per 1000 person-year and 15.0 per 1000 person-year, respectively. There was a significant increase in both the prevalence (Prevalence difference: 0.80, 95%CI 0.76–0.83%, P < 0.001) and the incidence of T2DM (Incidence difference: 0.9, 95%CI 0.7–1.1, P < 0.001). in Xiamen. The prevalence and incidence of T2DM in people aged 18–39 increased significantly (P < 0.001), while the prevalence and incidence of T2DM in people aged 40–69 reduced significantly (P < 0.001).ConclusionsThere was a significant increase in the prevalence and incidence of T2DM in Xiamen from 2014 to 2019 especially among those with younger age.

Highlights

The prevalence of diabetes is increasing worldwide
There was a significant increase in both the prevalence (Prevalence difference: 0.80, 95%Confidence interval (CI) 0.76–0.83%, P < 0.001) and the incidence of type 2 diabetes mellitus (T2DM) (Incidence difference: 0.9, 95%CI 0.7–1.1, P < 0.001). in Xiamen
In this study, we found that there was a significant increase in the prevalence and incidence rate of T2DM in

Summary

Results

Prevalence of T2DM in Xiamen In 2014, the resident population of Xiamen was 2,932, 637 and the number of T2DM patients was 118,468, with a prevalence of 4.04%. The number of newly diagnosed T2DM patients aged 50–59 years old was the largest, and the incidence rate was 30.4 per 1000 (95%CI, 29.8– 31.0). The incidence rate of T2DM was 2.6 per 1000 (95%CI, 2.5–2.7) at the age of 18–29 years old (Table 2; Fig. 2). The number of newly diagnosed T2DM patients aged 60–69 years old was 9732, with an incidence rate of 40.8 per 1000 (95%CI, 40.0–41.6). The incidence rate of newly diagnosed T2DM patients over the age of 70 years old was the highest in the same year, as high as 56.3 per 1000 (95%CI, 55.2–57.5). The incidence rate of T2DM increased with age in both men and women and increased sharply after the age of 50 years old. The prevalence of T2DM over 70 years old was the highest, as high as 2.64% (95%CI 2.26–3.01) (Table 3)

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Discussion

Conclusion