Abstract
BackgroundInsulin delivery triggered by a remote control is an advanced feature offered by newer insulin pump systems. These remote-integrated pump systems might further improve glycemic control and patient satisfaction. This study aims at assessing the effects of advanced insulin pump system on patients with type 1 diabetes mellitus (T1DM).MethodsThe prospective, observational study in two centers addressed patients on multiple daily injection (MDI) switching to an integrated pump system (primary: adolescents and young adults, secondary: school-children). Treatment and patient satisfaction parameters were recorded at baseline and at two visits at 12 and 24 weeks.ResultsThirty-eight patients were analyzed; primary n = 24 (mean-age 16) and secondary n = 14 (mean-age 9). From baseline to visit2, the mean decrease of HbA1c was 1.09% (p = 0.00009) and 0.79% (p = 0.09) for the primary and secondary group, respectively. Patient satisfaction rate was favorable. Exploratory analyses revealed patients favoring the use of the remote control achieved best reductions in HbA1c (p = 0.0174). Safety was encouraging with no adverse events in the period from visit1 to visit2.ConclusionsSwitching young T1DM patients from MDI to a remote control-integrated pump system achieved a reductions in HbA1c and insulin dose. Positive attitude towards remote operating enhanced these effects. Patient satisfaction has markedly improved.
Highlights
It is well known that in the treatment of type 1 diabetes mellitus (T1DM), continuous subcutaneous insulin infusion (CSII) by pump systems results in marked advantages compared to multiple daily injections (MDI) [1,2,3,4,5,6]
In two centers of the United Arab Emirates (UAE), paediatric T1DM patients were enrolled who were willing to switch from MDI to an integrated system of pump therapy featuring a bolus calculator and insulin release via remote control (ACCU-CHEK® Combo, ACC, Roche Diabetes Care, for clinical evaluations see ([25,26,27])
One Parent withdrew early and reverted to MDI as their 6-year-old child developed Diabetes ketoacidosis (DKA), another patient returned to MDI after 3 months for personal preference
Summary
It is well known that in the treatment of type 1 diabetes mellitus (T1DM), continuous subcutaneous insulin infusion (CSII) by pump systems results in marked advantages compared to multiple daily injections (MDI) [1,2,3,4,5,6]. Newer types of modern insulin pump have been used for treatment of T1DM. Insulin delivery triggered by a remote control is an advanced feature offered by newer insulin pump systems. These remote-integrated pump systems might further improve glycemic control and patient satisfaction. This study aims at assessing the effects of advanced insulin pump system on patients with type 1 diabetes mellitus (T1DM)
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