Abstract

Abstract This educational unit is developed to illuminate the inherent connections between cell communication and immunology through analysis of cell signaling in the context of an introduction to vertebrate immune responses. The students will gain knowledge of the two interrelated fields through a variety of lectures, written assignments, and a computer lab simulation, culminating in a final laboratory experiment entitled, “Determination of Antibody Concentrations by Modified ELISA”. Both the educational unit and the laboratory exercise are developed for a typical advanced high school AP Biology or second year biology course setting, budget, and equipment. Students will complete a macro-scale ELISA (Enzyme-linked Immunosorbent Assay) to provide hands-on experience with one of the most fundamental immunological assays used in modern research laboratories. Upon conclusion of this curriculum, students will have developed a deeper understanding of not only immunology and cell communication pathways, but also an appreciation for common laboratory tools in the fields of immunology and medicine.

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