Abstract
BackgroundHPV vaccination reduces the risk of cervical cancer. Uptake however, of the ‘catch-up’ campaign in England for 17-18 year old girls is below the 80% NHS target. The aim of this randomized controlled trial is to assess the impact of financial incentives on (a) the uptake and completion of an HPV vaccination programme and (b) the quality of the decisions to undertake the vaccination.Method/DesignOne thousand (n = 1000) 16-18 year-old girls will be invited to participate in an HPV vaccination programme: Five-hundred (n = 500) will have received a previous invitation to get vaccinated but will have failed to do so (previous non-attenders) and 500 will not have previously received an invitation (first-time invitees). Girls will be randomly selected from eligible participants who are registered with a GP in areas covered by the Birmingham East and North (BEN) and Heart of Birmingham Primary Care Trusts. The two samples of girls will be randomised to receive either a standard vaccination invitation letter or an invitation letter including the offer of vouchers worth £45 for receiving three vaccinations. Girls will also complete a questionnaire to assess the quality of their decisions to be vaccinated. The primary outcome will be uptake of the 1st and 3rd vaccinations. The secondary outcome will be the quality of the decisions to undertake the vaccination, measured by assessing attitudes towards and knowledge of the HPV vaccination.DiscussionThe key results will be: a) the effectiveness of financial incentives in increasing uptake of the 1st and 3rd vaccinations; b) the role of participants’ socio-economic status in the moderation of the impact of incentives on uptake; and c) the impact of incentives on the quality of decisions to undertake the HPV vaccinations.
Highlights
Human Papillomavirus (HPV) vaccination reduces the risk of cervical cancer
To be included in the trial, girls must fulfill the following inclusion criteria: (a) Live in areas falling under the administration of the Birmingham East and North (BEN) and the Heart of Birmingham Primary Care Trusts (b) Be registered with a GP within one of the two PCTs (c) Be eligible to be vaccinated through the clinics (Sutton Cottage, Partners in Health and Dove Medical Centre) (d) Not have been vaccinated against HPV before
CSI Health researchers will analyse the data with the aim of: i) determining the impact of financial incentives on uptake of the HPV vaccination and on the quality of girls’ decisions to get vaccinated; and ii) writing up and publishing the findings
Summary
Of the ‘catch-up’ campaign in England for 17-18 year old girls is below the 80% NHS target. The aim of this randomized controlled trial is to assess the impact of financial incentives on (a) the uptake and completion of an HPV vaccination programme and (b) the quality of the decisions to undertake the vaccination. A two-year ‘catch-up’ campaign that offers the HPV vaccine to 17-18 year old girls has been initiated The objective of these HPV vaccination programmes is to provide three doses of the HPV vaccine to females before they become sexually active, when the risk of HPV infection and subsequent cervical cancer development increases. The national programme in England aimed at 1213 year-old girls has resulted in high uptake
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