Abstract
One way of improving efficiency of research is to use core outcome sets, which allow results from different trials to be compared. Obtaining consensus over core outcome sets requires evidence on the validity, reliability and responsiveness of chosen measurement instruments. Re-using existing trial datasets to conduct validation studies of measurement instruments could be an efficient and timely means of filling known validation gaps.
Highlights
One way of improving efficiency of research is to use core outcome sets, which allow results from different trials to be compared
Using existing trial data to inform the development of core outcome sets and improve efficiencies in research
Using an exemplar from the field of eczema, evidence presented at meetings of the Harmonizing Outcome Measures for Eczema (HOME) initiative was reviewed, and included: qualitative surveys; systematic reviews of existing trials; and systematic reviews of validation studies
Summary
One way of improving efficiency of research is to use core outcome sets, which allow results from different trials to be compared. Using existing trial data to inform the development of core outcome sets and improve efficiencies in research Kim S Thomas1*, Lucy Bradshaw2, Alan A Montgommery2, Nick A Francis3, Matthew J Ridd4, Miriam Santer5
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