Year-end Sale % OFF 
Abstract
PurposeTo investigate the utility of the Corneal Visualization Scheimpflug Technology instrument (CST) to assess the progression of visual field (VF) damage in primary open angle glaucoma patients.MethodA total of 75 eyes from 111 patients with primary open-angle glaucoma were investigated. All patients underwent at least nine VF measurements with the Humphrey Field Analyzer, CST measurements, axial length (AL), central corneal thickness (CCT) and intraocular pressure (IOP) with Goldmann applanation tonometry (GAT). Mean total deviation (mTD) progression rates of the eight VFs, excluding the first VF, were calculated and the association between progression rate and the other listed measurements was analyzed using linear regression, and the optimal to describe mTD progression rate was selected based on the second order bias corrected Akaike Information Criterion (AICc) index.ResultsVF progression was described best in a model that included CST parameters as well as other ocular measurements. The optimal linear model to describe mTD progression rate was given by the equation: -8.9–0.068 x mean GAT + 0.68 x A1 time + 0.31 x A2 time -0.39 x A2 length– 1.26 x highest deformation amplitude.ConclusionCST measurements are useful when assessing VF progression in glaucoma patients. In particular, careful consideration should be given to patients where: (i) an eye is observed to be applanated fast in the first and second applanations, (ii) the applanated area is wide in the second applanation and (iii) the indentation is deep at the maximum deformation, since these eyes appear to be at greater risk of VF progression.
Highlights
Glaucoma is the leading cause of irreversible blindness worldwide with approximately 60 million people suffering from the disease[1]
The optimal linear model to describe Mean total deviation (mTD) progression rate was given by the equation: -8.9–0.068 x mean Goldmann applanation tonometry (GAT) + 0.68 x A1 time + 0.31 x A2 time -0.39 x A2 length– 1.26 x highest deformation amplitude
Careful consideration should be given to patients where: (i) an eye is observed to be applanated fast in the first and second applanations, (ii) the applanated area is wide in the second applanation and (iii) the indentation is deep at the maximum deformation, since these eyes appear to be at greater risk of visual field (VF) progression
Summary
Glaucoma is the leading cause of irreversible blindness worldwide with approximately 60 million people suffering from the disease[1]. Intraocular pressure (IOP) should be adequately controlled to avoid visual field (VF) deterioration.[2,3,4,5,6,7,8,9,10] Goldmann applanation tonometry (GAT) is widely considered the gold standard method to measure IOP in glaucoma patients. It is clear that the biomechanical properties of the cornea are a risk factor for the progression of glaucomatous neuropathy. Corneal biomechanics can be captured using the Corneal Visualization Scheimpflug Technology instrument (Corvis ST tonometry: CST; Oculus, Wetzlar, Germany). The biomechanical properties of the cornea can be assessed both visually and quantitatively.[26] to date, the relationship between CST parameters and glaucomatous VF progression has not been investigated in detail. The purpose of the current study is to investigate the importance of CST parameters on VF deterioration in patients with primary open angle glaucoma (POAG)
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
