Abstract

BackgroundThis paper reports on a study investigating the epidemiology of sporadic cryptosporidiosis in the North West of England and Wales using a Geographical Information System (GIS) to map location of residence of cases. Some 747 reports of cases were made to CDSC North West of which 649 reports were suitable for analysis. Cases were plotted on the maps of water supply zone and water quality area boundaries, provided by the two main water utilities.ResultsIt was notable that there were major spatial variations in attack rate across the North West and Wales. The most dramatic example was the large difference between the Greater Manchester conurbation with many reports and Liverpool with none. Given the distribution of previously detected waterborne outbreaks in the region it was initially thought that drinking water source may be an explanation. However, an analysis of the distribution of cases in the Greater Manchester area showed no correlation with any of five water supplies that serve the conurbation.ConclusionsOur study has shown a dramatic variation in the incidence of laboratory confirmed cryptosporidiosis within two regions of the United Kingdom. Further analysis has not been able to prove drinking water as a likely explanation of this variation which so far remains unexplained.

Highlights

  • This paper reports on a study investigating the epidemiology of sporadic cryptosporidiosis in the North West of England and Wales using a Geographical Information System (GIS) to map location of residence of cases

  • Outbreaks of cryptosporidiosis were a particular problem in the North West Region of England during the 1990s where a single unfiltered surface water source was responsible for several outbreaks [2]

  • Analysis was restricted to Greater Manchester as analysis of all reports in the North West could be subject to confounding as a result of geographical variation in reporting behaviour, whereas the Health Authorities in Greater Manchester share a very similar notification system

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Summary

Introduction

This paper reports on a study investigating the epidemiology of sporadic cryptosporidiosis in the North West of England and Wales using a Geographical Information System (GIS) to map location of residence of cases. Cryptosporidiosis is infection with species of the genus Cryptosporidium. Between the years 1983 to 1997 there were 80 outbreaks cryptosporidiosis in England and Wales affecting 4649 individuals [3]. Of these 80 outbreaks, 25 affecting 3455 cases were associated with drinking water. Outbreaks of cryptosporidiosis were a particular problem in the North West Region of England during the 1990s where a single unfiltered surface water source was responsible for several outbreaks [2]. Outbreak-related cases represent only a small proportion (

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