Abstract
Abstract Morelet et al. (1) assessed the usefulness of sequential urinary albumin measurements in 16 renal allograft recipients, eight with and eight without acute graft-rejection episodes. They concludedthat the urinary albumin/creatinine ratio is poorly specific in the diagnosis of acute renal rejection, as shown by a high proportion of false-positive results. In addition, they commented on similar findings-poor specificity and poor positive predictive value-for other urinary components, e.g., β2-microglobulin, neopterin, renal tubular enzymes, thromboxane B2 (TxB2), interleukin-2, and solubleIL-2 receptor.
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