Abstract

Background: Patients with spinal cord injury (SCI) are at increased risk for urinary tract infection (UTI) because of their neurogenic lower urinary tract dysfunction. It is unknown, however, what the prevalence of renal damage due to UTI is in SCI patients. Methods: Eleven SCI patients without UTI history and 41 SCI patients with UTI history only received technetium-99m dimercaptosuccinic acid ((superscript 99m)Tc-DMSA) renal cortex scan were included in this study to evaluate whether UTI influences the prevalence of renal damage in SCI patients. Results: Among 52 SCI patients, 33 (63.5%) of SCI patient had abnormal (superscript 99m)Tc-DMSA renal scan findings. The SCI patients with UTI history had a significantly higher prevalence of abnormal (superscript 99m)Tc renal cortex scan findings than those without UTI history (P value<0.05). Conclusion: We found that (superscript 99m)Tc-DMSA renal scan is a safe and noninvasive urological screening test to detect renal damage in SCI patients in this preliminary study.

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