Abstract
ABSTRACTIntroduction:The aim of this work is to study the density of the renal papillae in stone-forming patients and to determine its usefulness.Materials and Methods:This study included a total of 79 patients diagnosed with renal stones and on whom a computed tomography without contrast was performed from June 2014 to May 2015. The patients were divided into two groups: Group 1 (single episode) included 43 patients, and Group 2 (recurrent episodes) included 36 patients. The density of six renal papillae (3 per kidney) was measured, and the means obtained were compared between Groups 1 and 2. Statistical analysis was performed using SPSS 20.0.Results:The mean papillary density in Group 1 was 32.26 (SD 4.07) HU compared to 42.36 (SD 8.03) HU in Group 2 (P=00001). A ROC curve was constructed, obtaining an optimal cut-off point of 36.8HU [area under the curve, 0.881 (95% CI; 0.804-0.958); P=0001], with a sensitivity of 80% and a specificity of 90%. The relative risk was estimated at 40.3 (95% CI; 10.8-151.1), meaning that a patient with a mean papillary density greater than 36.8HU would have a 40 times greater risk of having recurrent renal stones. The positive predictive value (PPV) was 81% and the negative predictive value (NPV) was 90%.Conclusion:The measurement of renal papillary density could be useful in predicting recurrent stone-formers. These results need to be confirmed in future studies with a greater number of patients and a longer follow-up.
Highlights
The aim of this work is to study the density of the renal papillae in stoneforming patients and to determine its usefulness
In an attempt to find new applications for the measurement of HU in patients with renal stones, Ciudin et al [10] validated the theory of the Randall plaque due to the increased density of the renal papillae ibju | Hounsfiel unit and renal stone in renal stone-forming patients. It seems that the increase in density in renal papillae in stone-forming patients could be a warning sign of the subsequent development of a stone, or at least an indicator of lithogenic activity
A ROC curve was constructed in order to establish an optimum cut-off point in the papillary density (Figure-2), with a value of
Summary
The aim of this work is to study the density of the renal papillae in stoneforming patients and to determine its usefulness. Conclusion: The measurement of renal papillary density could be useful in predicting recurrent stone-formers. These results need to be confirmed in future studies with a greater number of patients and a longer follow-up. In an attempt to find new applications for the measurement of HU in patients with renal stones, Ciudin et al [10] validated the theory of the Randall plaque due to the increased density of the renal papillae ibju | Hounsfiel unit and renal stone in renal stone-forming patients. It seems that the increase in density in renal papillae in stone-forming patients could be a warning sign of the subsequent development of a stone, or at least an indicator of lithogenic activity
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