Abstract
IntroductionThe optimal suction pressure during endobronchial ultrasound guided transbronchial needle aspiration (EBUS-TBNA) remains to be determined. The aim of this study was to compare suction pressures for performance in collecting sufficient tissue specimens from mediastinal and hilar lymph nodes during EBUS-TBNA.MethodsRetrospective analysis of consecutive patients with mediastinal and hilar lymphadenopathy who underwent EBUS-TBNA over a 3-year period. Results from patients who underwent EBUS-TBNA using a dedicated 20-mL VacLoc (Merit Medical Systems, Inc, South Jordan, UT) syringe (conventional method, group C) were compared with results from patients in whom a disposable 30-mL syringe (high pressure group, group H) was used. The yield for sufficient histologic specimen retrieval and amount of tissue obtained were compared between the 2 groups.ResultsOf 178 patients who underwent EBUS-TBNA, 131 had lung cancer confirmed by EBUS-TBNA: 35 in group C and 96 in group H. There were 7 patients in group C and 6 in group H who received final diagnoses by cytology alone. There were 28 in group C and 90 in group H who were diagnosed by both cytology and histology. There was a statistically significant difference between the groups in terms of the rate of sufficient sampling for histological specimens (p = 0.04). The H group revealed a tissue area approximately twice that of the C group (p = 0.003). There were no major procedure-related complications in either group.ConclusionHigher suction pressures with larger syringe volumes during EBUS-TBNA may be useful for safely collecting sufficient tissue specimens.
Highlights
The optimal suction pressure during endobronchial ultrasound guided transbronchial needle aspiration (EBUS-TBNA) remains to be determined
Data were obtained from paper and electronic medical records, and patients were divided into 2 groups according to the volume of suction pressure used for specimen collection during EBUSTBNA
Patients who underwent EBUS-TBNA using the dedicated 20-mL VacLok syringe were in group C, and those in whom a disposable 30-mL syringe was used were in group H
Summary
The optimal suction pressure during endobronchial ultrasound guided transbronchial needle aspiration (EBUS-TBNA) remains to be determined. The aim of this study was to compare suction pressures for performance in collecting sufficient tissue specimens from mediastinal and hilar lymph nodes during EBUS-TBNA. Methods: Retrospective analysis of consecutive patients with mediastinal and hilar lymphadenopathy who underwent EBUS-TBNA over a 3-year period. Conclusion: Higher suction pressures with larger syringe volumes during EBUS-TBNA may be useful for safely collecting sufficient tissue specimens. Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a safe, minimally invasive diagnostic modality with a high yield for the diagnosis of mediastinal and hilar lymphadenopathy. Cytological and histological samples can be obtained by EBUS-TBNA, facilitating comprehensive evaluations such as immunohistochemistry and mutation analysis. The aim of this study was to assess the usefulness of high suction pressure for tissue aspiration during EBUS-TBNA. The optimal aspiration pressure for specimen collection by EBUS-TBNA remains unclear
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