Abstract

目的 评价增强后液体衰减反转恢复序列(FLAIR)在颅内肿瘤诊断中的应用价值.方法 104例颅内肿瘤,经手术、病理证实共有病灶124个.分别行增强前、后T1WI和FLAIR扫描.由2名有经验的放射科医生对所有病例进行评价.评价内容包括:增强例数、增强病灶个数及强化病灶部位;对比度及增强率;病变大小和范围.结果行统计学分析.结果 104例中,增强后FLAIR(CE FLAIR)成像、增强SE T1WI(CE T1WI)均显示98例有强化.CE FLAIR成像检出了117个强化灶,CE T1WI检出了120个.4个病灶仅在CE FLAIR显示而CE T1WI未显示.另有7个病灶仅在CE T1WI显示而CE FLAIR未显示.两者之信噪比(SNR)差异无统计学意义(t=1.10,P=0.270),脑灰白质对比度(GMC)、对比噪声比(CNR)及强化率(CER)差异均有统计学意义(t值分别为2.46、7.10、9.67,P值分别为0.015、0.000、0.000).在显示病灶大小上,CE FLAIR成像明显大于CE T1WI(t=4.13,P=0.000),在病灶范围上,有62例 CE FLAIR成像较CE T1WI大.CE FLAIR成像对位于脑沟、凸面、侧脑室旁及侧脑室内病灶的检出优于CE T1WI,而对大脑半球及第四脑室内的病灶的显示不如CE T1WI.结论 CE FLAIR成像与CE T1WI比较,强化病灶数,两者无明显差别,强化程度CE T1WI明显高于CE FLAIR成像,但两者对不同部位病灶的显示有明显差异,CE FLAIR成像显示病灶大小和范围明显大于CE T1WI.两种序列相互补充,建议将CE FLAIR成像序列列为增强后常规序列。

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