Abstract
Usefulness of CHA2DS2-Vasc Score for Hyperthyroid Patients with Atrial Fibrillation
Highlights
Atrial fibrillation (AF) is a well-established complication of hyperthyroidism with prevalence that can vary between 0.3% and 37.3%, depending on age, sex, and associated diseases [1]
This decision usually relies on the clinical risk score, CHA2DS2-VASc, which does not take into account any aspect of hyperthyroidism as a risk factor for an embolic event [4]
The clinical consequence of this hemostasis imbalance can be seen in case reports with central venous thrombosis, cerebral vasculitis, and disseminated intravascular coagulation, which support the concept of a pro-coagulant status related to hyperthyroidism, in Graves disease [7]
Summary
Atrial fibrillation (AF) is a well-established complication of hyperthyroidism with prevalence that can vary between 0.3% and 37.3%, depending on age, sex, and associated diseases [1]. One of the intriguing questions is the real risk of embolic events in patients with this condition. Evidence warranting anticoagulation treatment with warfarin for all patients with AF related to hyperthyroidism comes predominantly from case series or retrospective cohort trials [2,3]. Nowadays, this decision usually relies on the clinical risk score, CHA2DS2-VASc, which does not take into account any aspect of hyperthyroidism as a risk factor for an embolic event [4]
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