Abstract
Objectives: To investigate the effect of body mass index (BMI) on outcome of IVF/ICSI in Egyptian women withPCOS.Study design: Retrospective cohort study.Patients And Methods: The study included including 253 women with PCOS (study group) and 253 women with tubalor unexplained infertility (control group) that underwent IVF/ICSI treatment at Minia IVF Center in Egypt in the periodbetween January 2013 and December 2015.Results: The number of retrieved oocytes and the total number of embryos were significantly higher in women withPCOS compared to the control group (P=0.003 and 0.002 respectively). There was no significant difference betweenthe two groups as regards the clinical pregnancy rate (CPR), live birth rate and miscarriage rate. More cases of ovarianhyperstimulation syndrome (OHSS) were diagnosed in the PCOS group (24 vs. 5. P=0.3). When stratified for BMI,lean PCOS women (BMI< 25) had higher CPR (35% vs. 28.2, P=0.01), live birth rate (32% vs. 26.1%, P =0.01). Therewere more cases of OHSS in lean as compared with overweight and obese PCOS women (19% vs. 3.3%, P = 0.05).Conclusion: Lean PCOS women achieved higher CPR and live birth rate in IVF/ICSI compared to overweight andobese PCOS women in Egyptian population.
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