Abstract

The teaching of Molecular Biology in secondary schools suffers from student disengagement and lack of suitable resources to help students master this novel area of their curriculum. The result is frustration and incomprehension by the students. Visualization is critical for the learning of Molecular Biology. While the traditional classroom uses diagrams, models, and other tools to accommodate visual-spatial learners, these tools are insufficient to represent the cellular and molecular dynamics elucidated by current research and presented in the modern biology classroom. Several works have recommended the use of simulation-based learning environments. This chapter describes the design considerations in formulating an approach to help students “see” DNA, proteins, and cellular structures in three-dimensional space. The experimental study and intervention described leverage on novel computer-based virtual-reality technologies to help students understand the three-dimensional structures and the molecular interactions between them that enable function. Results indicate significant increases in Molecular Biology achievement in male students. Focus group interviews reveal that, prior to this intervention, students relied heavily on memorization, and the visualization exercises helped to clarify understanding while increasing interest and engagement. The results of this study recommend the use of technology in the teaching and learning of Molecular Biology, especially for male students in Singapore.

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