Abstract
Vaginal wall smears from 200 women with high-risk pregnancies (previous abortion, threatened abortion, reduced fertility, or unfavorable colpocytogram) correctly forecast the outcome of the pregnancy in 54 per cent of patients but in only 32 per cent of the 50 patients who aborted. Progesterone did not significantly reduce the rate of abortion. An initial favorable smear (84 patients) was associated with a successful pregnancy in 76 per cent of instances. The abortion rate for the entire group of 200 was 25 per cent, but, in 52 who had the combination of early bleeding and an unfavorable smear, 35 per cent aborted. Smears were judged on the basis of karyopyknotic index and a scoring of navicular cells, wrinkling, and clumping. A colpocytogram is not a reliable predictor of pregnancy outcome in the individual patient.
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