Abstract
The morphological transformation of Syrian hamster embryo (SHE) cells has been used for the in vitro testing of the transforming activity of five pesticides (Dual, Vucht 524, Piritione, Decemtione and Supercypermethrin). Morphological transformation with two known inducers, 3-methylcholanthrene and N-methyl- N‘-nitro- N-nitrosoguanidine, was used as a positive control. It was found that only one of the tested pesticides, Dual, failed to induce morphological transformation in SHE cells, whereas the remaining four demonstrated varying degrees of positive response and could be regarded as potential carcinogenic chemicals.
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