Abstract

Congenital or acquired hypogonadotropic hypogonadism (HH) is an important cause of anovulatory infertility. In functional hypothalamic amenorrhea (FHA), loss of function of the hypothalamichypopituitary axis occurs in catabolic states induced by eating disorders, compulsive exercise and high levels of somatic or psychological stress [1]. In patients with FHA attempting to conceive, in addition to addressing the underlying cause, a subcutaneous pulsatile gonadotropin releasing hormone (GnRH) pump may be used to induce ovulation [2].

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