Use of the handheld ultrasound-guided basket Intact Breast Lesion Excision System for the excision of breast cancers from patients suitable for primary endocrine therapy: Is this technically feasible?

Abstract

Introduction: The handheld Intact Breast Lesion Excision System (Intact) allows radiological excision of an entire breast lesion under ultrasound (USS) guidance for diagnosis and margin assessment. Its use excising benign breast lesions is established, and we have presented data demonstrating it as a reliable and effective tool in this context. The treatment of patients with primary endocrine therapy (PET) is the cause for debate, in particular whether denying surgical excision adversely affects outcome. The aim of the current study was to determine the feasibility of Intact excision of breast cancers from these patients.