Abstract
The putative intermediate bis(1,2,4-triazolide) derivative (5) is used in the stepwise synthesis in solution of the phosphorodithioate analogue ( 10 ) of thymidylyl-(3′→5′)-thymidylyl-(3′→5′)-thymidine; the 2,4-dinitrobenzyl (Dnb) group is used to protect phosphorodithioate internucleotide linkages.
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