Abstract

In our Trust, all breast cancer patients undergo preoperative axillary staging with ultrasound. Over the past year we have introduced intradermal sulphur hexafluoride microbubbles ultrasound contrast injection to help identify sentinel lymph nodes for a preoperative needle biopsy in each patient. Only patients with malignant node morphology on grey-scale ultrasound undergo biopsy without microbubbles injection.

Highlights

  • The aim was to compare the accuracy of standard supplementary views and GE digital breast tomosynthesis (DBT) for assessment of soft tissue mammographic abnormalities

  • The measured parameter is the volume averaged speed of sound (VASS) [1,2]. It improves on mammography by measuring density at each voxel and holds promise as a cheap, patient-acceptable, non-ionising radiation method to evaluate density

  • This study was to evaluate the technique of Ultrasound tomography (UST) and compare VASS with percentage water density from non-contrast magnetic resonance imaging (MRI)

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Summary

Introduction

The aim was to compare the accuracy of standard supplementary views and GE digital breast tomosynthesis (DBT) for assessment of soft tissue mammographic abnormalities. Methods: Prospective audit of data collated at the time of the microbubbles procedure together with multidisciplinary meeting records identified relevant screening and symptomatic patients with primary breast cancer treatment including axillary node surgery between 1 July 2014 and 1 July 2015. Breast MRI can be performed in the preoperative workup of patients with biopsy-proven breast cancer to size lesions, if there is discrepancy regarding the extent of disease from clinical, mammography or ultrasound assessment, and to identify multicentric or multifocal disease. Conclusion: MRI is more sensitive than the other three imaging modalities combined in accurately identifying multifocal breast cancer; DBT is still a useful adjunct in the evaluation of multifocal disease. Retrospective review of 399 patients who underwent biopsy for breast microcalcification during screening assessment from April 2012 to March 2013 was used to evaluate the performance and cost-effectiveness of both methods. Radiologist time may be better directed towards meeting the symptomatic breast 2-week wait standard

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