Use of Selective Pulmonary Vasodilators to Treat Pulmonary Arterial Hypertension Prior to Successful Surgical Closure of Atrial-Level Shunts

Abstract

Background: Significant pulmonary hypertension [PH] is often considered a contraindication for closure of atrial septal defects [ASD]. Treatment of pulmonary arterial hypertension [PAH] with selective pulmonary vasodilators can allow for surgical repair of ASD otherwise considered prohibitive. We describe our experience in the assessment and treatment of adults with ASD and PAH with pulmonary vasodilator therapy who underwent successful surgical repair.