Abstract
Aim: Data on the real-world use of hyaluronidase-facilitated subcutaneous 10% immunoglobulin (fSCIG; HyQvia®) in elderly patients with primary or secondary immunodeficiencies (PID or SID) are unreported. This study determined real-world patterns from one administration of fSCIG. Materials & methods: In this retrospective, multicenter study, medical records of patients aged ≥65years with PID or SID were reviewed. Results: The majority of patients (mean age: 69.9years) with PID (n=10) or SID (n=6) self-administered fSCIG (200-350ml) at home every 3-4weeks using a single infusion site by infusion pump at rates up to 300ml/h. Conclusion: This study provides initial real-world evidence supporting home-based, self-administration of large volumes of fSCIG in elderly patients with PID or SID.
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