Use of post-mortem computed tomography during the COVID-19 pandemic

Abstract

Post mortem computed tomography (PMCT) is widely used in England and Wales to supplement or replace traditional invasive Coroner's autopsy. Using PMCT and coronary angiography, the cause of death can be determined without invasive examination in approximately 70% of cases, assuming a typical Coroner's autopsy case mix. Coroner's autopsy services continued during the COVID-19 pandemic and have identified deaths resulting from COVID-19 undiagnosed in life. In some areas of England, PMCT was used to replace traditional autopsy due to concerns over infection risk to mortuary staff associated with invasive autopsy. Health and safety concerns also resulted in changes to post mortem scanning protocols. PMCT has been used to identify potential COVID-19 deaths and assist in the selection of cases for viral studies. There is typically bilateral ground-glass opacities and consolidation within the lungs on CT; although these changes are not specific for COVID-19, the diagnosis can be confirmed with post mortem nose and throat swabs.