Use of planar kV vs. CBCT in evaluation of setup errors in oesophagus carcinoma radiotherapy

Abstract

AimThe aim of this study is to evaluate differences in terms of the setup errors observed using kV planar image compared to CBCT for oesophageal cancer patients. BackgroundPlanar kV images are quick to acquire but only allow the observation of bony structures. CBCT allows the evaluation of soft tissues, which includes the oesophagus (and tumour) and OAR, giving a more accurate verification of the positioning. Materials and MethodsAll patients were imaged with both techniques between January 2012 and March 2014 were included in the study (16 patients, 212kV images and 116 CBCT images). Differences between the setup errors observed on the two images modalities were studied. A correlation study between TNM staging, tumour location and immobilization systems with setup errors was also done. Finally, the calculation of systematic and random errors allowed to determine the CTV–PTV margin. ResultsA significant discrepancy (p<0.05) between the setup errors observed with kV and CBCT was observed in the lateral direction. No statistical correlation was found between setup errors and tumour location, immobilization system or TNM staging. The CTV–PTV margin was smaller with CBCT in the vertical (0.6cm vs. 0.9cm) and longitudinal (0.7cm vs. 1cm) directions and smaller with kV for the lateral directions (0.8cm vs. 0.9cm). ConclusionsThe chosen modality influences the setup error observed which will influence the correction applied. Allowing a better observation of the volumes of interest, CBCT should be the modality of choice in this pathology. The CTV–PTV margins could be shrunk if CBCT is used.