Abstract
In the face of controversies about the treatment of tendon injuries, non-surgical treatment using photobiomodulation therapy has been shown to be effective in repair. Objective was to evaluate the effects of photobiomodulation therapy on the tendon repair process. 42 Rattus norvegicus belonging to the wistar lineage were used, which were randomly divided into 2 experimental groups: Control (CG); Photobiomodulation (PBM). The groups were subdivided into 3 experimental periods: 7, 14 and 21 days. PBM started 24 hours after injury induction and followed for 7, 14, 21 days. For FBM, the 660 nm, 40 mW, 0.23 J and 6 s laser was used. The volume of the edema was evaluated, immediately before the tendon transection; 24 hours later; on the day of euthanasia, following their respective experimental periods. Histopathological analysis of the region of the transect and the quantification of blood vessels were performed using HE. Edema results: 24 hours after injury induction, there was no statistical difference between the experimental groups. After the experimental periods, 7, 14 and 21 days, the PBM group was effective in reducing the edema compared to the control. Histological results revealed that the PBM group had a greater tendon injury compared to the control after 7 days. After 14 and 21 days, the PBM group showed a better repair process compared to the control group. Likewise, PBM showed a greater number of blood vessels when compared to the control, after all experimental periods. The PBM treatment was effective in reducing the volume of the edema, preventing degenerative morphological alterations of the tendon, after 21 days.
Highlights
Trata-se de uma pesquisa experimental, com a finalidade de obter uma constatação cientifica, utilizando-se para tal, procedimentos que visam responder os objetivos do estudo em questão (Pereira et al, 2018)
42 Rattus norvegicus belonging to the wistar lineage were used, which were randomly divided into 2 experimental groups: Control (CG); Photobiomodulation (PBM)
The groups were subdivided into 3 experimental periods: 7, 14 and 21 days
Summary
As lesões musculoesqueléticas causam um ônus significativo para a sociedade e podem ter um impacto considerável na morbimortalidade do paciente. Os grandes tendões que apresentam uma alta demanda de carga, como o tendão calcâneo, normalmente são os mais acometidos e estas lesões tendíneas estão entre os problemas ortopédicos mais comuns (Karaaslan et al, 2016). Apesar dos dados encorajadores sobre os efeitos potenciais da FBM no tratamento de ruptura de tendão ainda não são totalmente compreendidos. O presente estudo teve como objetivo avaliar o efeito da terapia por fotobiomodulação no processo de reparo tendíneo
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
