Abstract

Background: Palifermin is a recombinant keratinocyte growth factor (KGF) approved to decrease the incidence and severity of mucositis in stem cell transplantation. Furthermore, effects on the KGF receptor may modulate and minimize acute GVHD. Studies utilizing palifermin have been conducted in autologous SCT; however, literature regarding use in allogeneic SCT is minimal.

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