Use of Ovostim-CT in the prevention of hepatosis and retention of placenta in cows after calving

P.V Burkov,O Loretts,V Kukhar,A Ruchkin,O Nazarova,M Karpukhin

doi:10.1051/e3sconf/202128203014

Abstract

High milk productivity of cows after calving is the cause of liver damage in the form of hepatosis and premature retirement of animals. In such cases, a pathological examination simultaneously reveals violations in the form of protein and fatty degenerations with the subsequent destruction of cells, as well as disturbed circulation in the liver. Also, hepatoses can cause such postpartum complications in cows as retention of placenta. For the prevention of hepatosis, the drug “Ovostim-ct” is proposed, which contains cytotoxic sera against the tissues of the liver, ovary, spleen and muscle. In order to prevent liver damage and postpartum retention of placenta, the drug is used 1-1.5 months before calving at a dose of 1 ml per 100 kg of live weight subcutaneously or intramuscularly. The use of the hepatoprotector allowed to reduce the number of cases of hepatosis and retention of placenta in cows after calving. Also, “Ovostim-ct” had a favorable effect on the biochemical parameters of the blood serum of cows: there was an increase in the concentration of total protein by 6.7%, albumin - by 15.6% and glucose - by 45.8% in the blood.

Highlights

Due to the high potential of milk productivity, intense metabolism in the transit period and immediately after calving, the liver in cows after calving is subject to significant stresses, which in most cases lead to forced culling and premature slaughter
The content of total protein, albumins, and glucose was determined in the blood serum
The method is based on the interaction of albumins with bromocresol green in a slightly acidic medium in the presence of a detergent, which is accompanied by the formation of a colored blue compound, the color intensity of which is proportional to the concentration of albumins

Summary

Introduction

Due to the high potential of milk productivity, intense metabolism in the transit period and immediately after calving, the liver in cows after calving is subject to significant stresses, which in most cases lead to forced culling and premature slaughter. In this regard, agricultural enterprises suffer significant losses, since the cow can not even justify the costs of its cultivation. With the modern technology of milk production, associated with a sufficiently high level of animal feeding, it is almost impossible to create ideal conditions for maintaining health and productive longevity. The liver in cows is damaged by infectious diseases [1-8]

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