Abstract

saline and ipratropium bromide. There was no change in specific conductance after nebulised normal saline. In the group as a whole there was a significant decrease in specific conductance at one minute after nebulisation of the ipratropium bromide (from a mean of 0-083/cmH20/s to 0-066/cmH2O/s; p<0 05). Twenty minutes after nebulisation of ipratropium bromide specific conductance was significantly greater (0 11 cm H20/s) than baseline values (p<005). The osmolality of nebulised normal saline changed from 280 to 320 mmol/kg during nebulisation and that of the nebulised ipratropium bromide from 285 to 318 mmol/kg. There was no change in the pH of the solutions with nebulisation.

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