Abstract
Nicotine replacement therapies (NRT), in the form of nicotine patch, gum, lozenge, nasal spray and inhaler, are primarily licensed as aids to long-term smoking cessation. The evidence that they are safe and effective at increasing smokers' chances of long-term quitting is very solid (1,2). It is also clear that one important mechanism of action of NRTs is that they reduce the severity of nicotine withdrawal symptoms and cravings to smoke (3,4).
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