Abstract
Near-infrared spectroscopy (NIRS) is a technology capable of non-invasive, continuous measuring of regional tissue oxygen saturation (StO2). StO2 represents a state of hemodynamic stability, which is influenced by many factors. Extensive research has been done in the field of measuring StO2 of various organs. The current clinical availability of several NIRS-based devices reflects an important development in prevention, detection and correction of discrepancy in oxygen delivery to the brain and vital organs. Managing cerebral ischemia remains a significant issue in the neonatal intensive care units (NICU). Cerebral tissue oxygenation (cStO2) and cerebral fractional tissue extraction (cFTOE) are reported in a large number of clinical studies. This review provides a summary of the concept of function, current variability of NIRS-based devices used in neonatology, clinical applications in continuous cStO2 monitoring, limitations, disadvantages, and the potential of current technology.
Highlights
Non-invasive measurement of cerebral tissue oxygenation using near-infrared spectroscopy (NIRS) is attracting increasing attention in neonatology[1]
This review provides a summary of the concept of function, current variability of NIRS-based devices used in neonatology, clinical applications in continuous cStO2 monitoring, limitations, disadvantages, and the potential of current technology
The aim of this review is to provide a summary of the relationship between cStO and immediate postnatal adaptation, hypoxic-ischemic encephalopathy (HIE), patent ductus arteriosus (PDA), intraventricular hemorrhage (IVH), and respiratory distress syndrome (RDS), and to describe the clinical relevance of this method
Summary
Non-invasive measurement of cerebral tissue oxygenation using near-infrared spectroscopy (NIRS) is attracting increasing attention in neonatology[1]. NIRS provides a continuous assessment of regional cerebral oxygenation (cStO ), and cerebral tissue oxygen extraction (cFTOE). It is not seen as a routine brain monitoring tool in neonatal intensive care units (NICU) (ref.[2,3]). The review summarizes the mode of function, current variability of NIRS-based devices used in neonatology, clinical applications of continuous monitoring of cerebral tissue oxygenation. It covers the limitations and disadvantages of current technology and ends with the potential of such technology if implemented in NICU environment
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