Use of Mononuclear Leukocyte Insulin Receptor Characteristics as Predictors of Carcass Composition in Heifers and Steers

Abstract

Total insulin specific binding (IB) and the number and affinity of insulin receptors on mononuclear leukocytes (MNL) were used to predict carcass composition of heifers and steers. Dependent variables were kidney fat, body cavity fat, s.c. fat, intermuscular fat, lean and bone. Independent variables were parameters that could be measured on the live animal, including insulin receptor characteristics, age, shrunk weight, breed and carcass s.c. rib fat thickness (SUB). All carcass fat characteristics and IB were greater for heifers than for steers, but the ability to predict either heifer or steer carcass fat characteristics was not improved by inclusion of IB in prediction equations. However, the number of low-affinity insulin receptors on MNL contributed significantly to the prediction of all heifer carcass characteristics except bone. Carcass s.c. rib fat thickness also entered the prediction equations for all heifer carcass characteristics except kidney fat. In the prediction of heifer kidney fat, the only significant independent variable was the number of low-affinity insulin receptors on MNL (R2 = .38). Carcass characteristics of steers were better predicted by SUB than were heifer carcass characteristics, and insulin receptor characteristics, when added to steer equations that contained SUB, improved R2 by .10 or less. Our results suggest that insulin receptor characteristics will be most useful in the prediction of carcass characteristics of heifers where there is a poor relationship between quantity of s.c. fat and other carcass fat depots.