Abstract

PurposeTo describe our initial experience with use of microspheres in transcatheter arterial embolization (TAE) for unruptured sporadic renal angiomyolipomas (AMLs).Materials and methodsSeven consecutive patients with seven unruptured sporadic renal AMLs, 6 females and 1 male, with a median age of 45 years (range, 30–69 years), underwent TAE using microspheres between November 2016 and February 2020. We evaluated the technical success rate, complications related to the procedure, clinical success rate, and the shrinkage rate of renal AML. Technical success was defined as the completion of TAE. Clinical success was defined as presence of shrinkage of the renal AML after TAE.ResultsIn all patients, TAE using microspheres was accomplished and technical success rate was 100% (7/7). Three patients exhibited slight pain, but it improved with only observation, and the minor complication rate was 43% (3/7) and major complication rate was 0% (0/7). After the TAE, shrinkage of renal AML was confirmed in 6 of 7 patients, and clinical success rate was 86% (6/7). The median of shrinkage rate was 47% (range, 26–83%) with a median follow-up period of 19 months (range, 4–30 months).ConclusionTAE using microspheres appears to be effective and safe for unruptured sporadic renal AMLs.

Highlights

  • Renal angiomyolipomas (AMLs) are benign tumors composed of differing degrees of fat, smooth muscle, and abnormal blood vessels and have a propensity to bleed [1,2]

  • Polyvinyl alcohol (PVA) particles were widely used to embolize renal AMLs [8,9,10], but they aggregate due to their irregular shape and size variability [11]

  • We describe our initial experience with the use of microspheres in Transcatheter arterial embolization (TAE) for unruptured sporadic renal AML

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Summary

Introduction

Renal angiomyolipomas (AMLs) are benign tumors composed of differing degrees of fat, smooth muscle, and abnormal blood vessels and have a propensity to bleed [1,2]. Ethanol has been widely used as embolic material in TAE [5,6]. Polyvinyl alcohol (PVA) particles were widely used to embolize renal AMLs [8,9,10], but they aggregate due to their irregular shape and size variability [11]. Microspheres have recently become available in our country They are precisely calibrated by size, and smoother and more spherical in shape, without fragmentation, than PVA particles [7]. This prevents particle aggregation, thereby allowing the microspheres to better penetrate into smaller vessels than PVA particles of the same size.

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