Abstract
The main cause of death in the intensive care units is infectious complications, including sepsis and septic shock. Immunoglobulins are the most potent mechanisms in anti-infective defense. Whether intravenous immunoglobulins should be used in urgent situations remains to be solved. The mechanisms of action of immunoglobulins are diverse and depend on dosage and time of use. The paper analyzes the data available in the Russian and foreign literature on the possible points of use of intravenous immunoglobulins in the treatment of acute conditions accompanied by sepsis. It also gives the authors’ data on the use of intravenous immunoglobulins to treat toxic epidermal necrolysis. Key words: intravenous immunoglob-ulins, sepsis, toxic epidermal necrolysis.
Highlights
Основной причиной смерти в отделениях интенсивной терапии являются инфекционные осложнения, в том числе сеп сис и септический шок
Whether intravenous immunoglobulins should be used in urgent situations remains to be solved
The paper analyzes the data available in the Russian and foreign literature on the possible points of use of intravenous immunoglobulins in the treatment of acute conditions accompanied by sepsis
Summary
Основной причиной смерти в отделениях интенсивной терапии являются инфекционные осложнения, в том числе сеп сис и септический шок. Use of Intravenous Immunoglobulins in Intensive Therapy Приведены данные собственного опыта использования внутривенных иммуноглобулинов при лечении токсико эпидермального некролиза. It gives the authors' data on the use of intravenous immunoglobulins to treat toxic epidermal necrolysis.
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