Use of Injectable Hyaluronic Acid Gel and Injectable Platelet-rich Fibrin in the Treatment of Gingival Black Triangles: A Randomized Clinical Trial

Abstract

Purpose: The current study aimed to compare the efficacy of injectable hyaluronic acid gel and injectable platelet rich fibrin, either alone or combined; for the reconstruction of defective interdental papilla using clinical approaches. Subjects and Methods: A total sample size of eighteen class I and class II deficient interdental papillae sites were randomly divided in 3 groups. Group 1 included 6 sites that were treated by 0.2ml hyaluronic acid gel injection. Group 2 included 6 sites that were treated by injectable platelet-rich fibrin (i-PRF). Group 3 included 6 sites that were treated by a combination of 0.2ml hyaluronic acid gel injection and iPRF. Each deficient papilla received 3 injections; at 0, 3and 6 weeks intervals. The height of black triangles was recorded at baseline before injection procedure, at each injection interval and during follow ups. Results: A statistically significant difference in all three groups was found in the mean of the black triangle height records between the five time intervals, mainly between baseline and 6 months follow up. Conclusion: Hyaluronic acid injections and injectable platelet rich fibrin can be an alternative non-invasive treatment method for gingival black triangles.