Abstract
The diabetogenic potency of 10 mg. of human growth hormone and of 100 mg. of cortisone acetate was studied in five normal volunteers. Measurements of glucose, free fatty acids, immunoreactive insulin and immunoreactive growth hormone following a carbohydrate load revealed that twelve hours after a single intramuscular dose of growth hormone impairment of glucose tolerance and elevation in both serum insulin and free fatty acids were evident. Cortisone alone resulted in minimal changes in these indices, and the combination of cortisone and growth hormone was similar in effect to growth hormone alone. Concentrations of growth hormone in serum were still elevated twelve to fifteen hours after the intramuscular administration of a single 10 mg. dose.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
