Use of Gentian Violet in the Treatment of Severe Radiodermatitis Secondary to Adjuvant Radiotherapy in Breast Cancer

Abstract

Adjuvant radiotherapy is indicated for patients with conservatively or radically operated breast cancer, demonstrating the benefit of this type of treatment for local recurrence rate and survival. Radiodermatitis are radiation-induced skin reactions, a significant side effect of cumulative ionizing radiation in significant doses at the skin level during the treatment of various tumor localizations. This study presents aspects regarding prevention and treatment of radiodermatitis in patients with adjuvant irradiated breast cancer treated in the Regional Institute of Oncology Iasi. In the study group, use of gentian violet has helped to alleviate these side effects of irradiation, both in intensity and duration, with an important impact on the quality of life of the patients.