Abstract
ABSTRACT: The effects of acetate as an alkalinizing agent in maintenance enteral electrolyte solutions administered by nasogastric route in a continuous flow have not been previously described in weaned foals. This is the second part of a study that evaluated the effects of two electrolyte solutions of enteral therapy fluid in weaned foals. In this part, will be considered the effects of enteral electrolyte solutions containing different acetate concentrations on acid-base balance, blood glucose, lactate and urine pH of weaned foals. This was a controlled trial in a cross-over design performed in six foals with a mean age of 7.3 ± 1.4 months. After 12 h of water and food deprivation, each animal received the following two treatments by nasogastric route in a continuous flow of 15 ml/kg/h during 12 h: HighAcetate (acetate 52 mmol/l) and LowAcetate (acetate 22.6 mmol/l). The HighAcetate treatment was effective in generating a slight increase in blood pH, blood bicarbonate concentration, base excess and urinary pH.
Highlights
Foals with colitis and diarrhea often develop acid-base imbalances with metabolic acidosis being the most prevalent disorder (GOMEZ et al, 2013; GOMEZ; et al, 2015; KOTERBA; et al, 1984)
The correction of hydro electrolytic and acid-base imbalances can be achieved through fluid therapy with crystalloid solutions administered by the parenteral or enteral route
Glucose and lactate findings are described in table 2, and urinary pH is in table 3
Summary
Foals with colitis and diarrhea often develop acid-base imbalances with metabolic acidosis being the most prevalent disorder (GOMEZ et al, 2013; GOMEZ; et al, 2015; KOTERBA; et al, 1984). The correction of hydro electrolytic and acid-base imbalances can be achieved through fluid therapy with crystalloid solutions administered by the parenteral or enteral route. The intravenous route enables a fast plasma volume expansion desirable in cases of severe dehydration and acid-base disbalance but requires the use of commercially available sterile solutions. In patients with mild to moderate dehydration and base acid imbalances, and normal function of the gastrointestinal tract, enteral hydration is an effective. The parenteral commercial electrolytic solutions do not have the appropriate composition to correct certain electrolytic and acid-base imbalances. Enteral electrolyte solutions can be precisely adjusted in their composition according to the electrolyte requirements of patients. Enteral hydration may be a more appropriate option for certain pathological conditions
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